MovDisordV3, Main, Exploration, bibRecord, 001141

Dopamine Agonists and Delusional Jealousy in Parkinson's Disease: A Cross-Sectional Prevalence Study

Identifieur interne : 001141 ( Main/Exploration ); précédent : 001140; suivant : 001142

Dopamine Agonists and Delusional Jealousy in Parkinson's Disease: A Cross-Sectional Prevalence Study

Auteurs : Michele Poletti [Italie] ; Giulio Perugi [Italie] ; Chiara Logi [Italie] ; Anna Romano [Italie] ; Paolo Del Dotto [Italie] ; Roberto Ceravolo [Italie] ; Giuseppe Rossi [Italie] ; Pasquale Pepe [Italie] ; Liliana Dell'Osso [Italie] ; Ubaldo Bonuccelli [Italie]

Source :

Movement disorders [ 0885-3185 ] ; 2012.

RBID : Pascal:13-0017947

Descripteurs français

Pascal (Inist)
- Délire, Maladie de Parkinson, Démence, Pathologie du système nerveux, Stimulant dopaminergique, Etude transversale, Prévalence, Lévodopa.

English descriptors

KwdEn :
- Cross sectional study, Delusion, Dementia, Dopamine agonist, Levodopa, Nervous system diseases, Parkinson disease, Prevalence.

Abstract

Background: Delusional jealousy (DJ) has been described in patients with Parkinson's disease (PD) on dopaminergic therapy, but a role for dopaminergic therapy in DJ has not been established. Methods: The current cross-sectional study on DJ investigated its association with dopaminergic therapies compared with their associations with hallucinations and its prevalence in PD patients. Eight hundred five consecutive patients with PD were enrolled between January 2009 and June 2010. Results: DJ was identified in 20 patients (2.48%) and hallucinations in 193 patients (23.98%). In the multivariate logistic regression analyses, dopamine agonists were significantly associated with DJ (odds ratio, 18.1; 95% CI, 3.0-infinity; P = .0002) but not with hallucinations (odds ratio, 0.73; 95% CI, 0.49-1.10; P = .133). Conclusions: These findings suggest that dopamine agonist treatment represents a risk factor for DJ in PD independent of the presence of a dementing disorder, and the presence of this additional nonmotor side effect should be investigated in this clinical population.

Affiliations:

Italie

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Le document en format XML

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<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cross sectional study</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Délire</term>
<term>Maladie de Parkinson</term>
<term>Démence</term>
<term>Pathologie du   système nerveux</term>
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<front><div type="abstract" xml:lang="en">Background: Delusional jealousy (DJ) has been described in patients with Parkinson's disease (PD) on dopaminergic therapy, but a role for dopaminergic therapy in DJ has not been established. Methods: The current cross-sectional study on DJ investigated its association with dopaminergic therapies compared with their associations with hallucinations and its prevalence in PD patients. Eight hundred five consecutive patients with PD were enrolled between January 2009 and June 2010. Results: DJ was identified in 20 patients (2.48%) and hallucinations in 193 patients (23.98%). In the multivariate logistic regression analyses, dopamine agonists were significantly associated with DJ (odds ratio, 18.1; 95% CI, 3.0-infinity; P = .0002) but not with hallucinations (odds ratio, 0.73; 95% CI, 0.49-1.10; P = .133). Conclusions: These findings suggest that dopamine agonist treatment represents a risk factor for DJ in PD independent of the presence of a dementing disorder, and the presence of this additional nonmotor side effect should be investigated in this clinical population.</div>
</front>
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<name sortKey="Rossi, Giuseppe" sort="Rossi, Giuseppe" uniqKey="Rossi G" first="Giuseppe" last="Rossi">Giuseppe Rossi</name>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Dopamine Agonists and Delusional Jealousy in Parkinson's Disease: A Cross-Sectional Prevalence Study

Dopamine Agonists and Delusional Jealousy in Parkinson's Disease: A Cross-Sectional Prevalence Study

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri